DNA Vaccines Against Viral Diseases of Aquaculture
Abstract: Deoxyribonucleic acid (DNA) vaccination is the administration of the gene encoding the antigen and
consequently, the antigen expression by cells in the vaccinated hosts and triggering the host immune system.
DNA fish vaccines against viral pathogens had limited success and most efficient delivery route is IM injection. Suitable delivery strategies must be developed for mass vaccination of small fish. DNA vaccinations against fish viral diseases against IHNV and VHSV at commercial level proved to be successful. DNA vaccine technology could provide a valuable tool for more sustainable production of improved farmed fish, reduced environmental impacts of aquaculture activities, increased food quality and quantity.
Kawther S. Zaher (1) and Wahid M. Ahmed (2)
1Department of Microbiology and Immunology, National Research Centre, Dokki, Egypt
2Department of Animal Reproduction & AI, National Research Centre, Dokki, Egypt
Advances in Biological Research 10 (5): 348-350, 2016
© IDOSI Publications, 2016